Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.64 |
| ▸ | PRKCI | P41743 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598196 | 0.86 | ADORA1 (0.43) | ADORA1KDM4EMAPT | |
| SCHEMBL9597904 | 0.85 | BPTF (0.46) | ADORA1PRKCIKDM4EMAPT | |
| SCHEMBL9598034 | 0.82 | PRKCI (0.48) | ADORA1PRKCIKDM4EMAPTP2RX3 | |
| SCHEMBL9599417 | 0.81 | KDM4E (0.57) | ADORA1KDM4EMAPT | |
| SCHEMBL4059322 | 0.79 | P2RX3 (0.52) | ADORA1PRKCIP2RX3MKNK1 | |
| SCHEMBL3499018 | 0.78 | ADORA1 (1.00) | ADORA1KDM4EMAPTP2RX3MKNK1 | |
| SCHEMBL9603759 | 0.78 | GABRP (0.41) | ADORA1KDM4EMAPT | |
| SCHEMBL27302182 | 0.78 | ADORA1 (0.77) | ADORA1KDM4EMAPTP2RX3MKNK1 | |
| SCHEMBL7885804 | 0.77 | MKNK1 (0.49) | ADORA1PRKCIKDM4EP2RX3MKNK1 | |
| SCHEMBL618092 | 0.74 | MAPT (0.54) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5268007-A | Containing carbamate group | THE LUBRIZOL CORPORATION (US) | 1993-12-07 | — | — | US | disclosed |
| WO-1993013104-A1 | C.N.S. ACTIVE TRICYCLIC THIENOPYRIDINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1993-07-08 | — | — | WO | disclosed |
| US-5093018-A | Dioxolanes and thio analogs, derivatives thereof and lubricants and fuels containing same | THE LUBRIZOL CORPORATION (US) | 1992-03-03 | — | — | US | disclosed |
| EP-0295298-B1 | DIOXOLANES AND THIO ANALOGS, DERIVATING THEREOF AND LUBRICANTS AND FUELS CONTAINING SAME | The Lubrizol Corporation (US) | 1991-10-23 | — | — | EP | disclosed |
| US-4906253-A | Dioxolanes and thio analogs, derivatives thereof and lubricants and fuels containing same | THE LUBRIZOL CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0295298-A1 | DIOXOLANES AND THIO ANALOGS, DERIVATING THEREOF AND LUBRICANTS AND FUELS CONTAINING SAME. | LUBRIZOL CORP (US) | 1988-12-21 | — | — | EP | disclosed |
| US-4792411-A | Dioxolanes and thio analogs, derivatives thereof and lubricants and fuels containing same | THE LUBRIZOL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |