Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 7/20 | 0.41 |
| ▸ | GABRD | O14764 | 7/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.41 |
| ▸ | GABRE | P78334 | 7/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9599417 | 0.85 | KDM4E (0.57) | MAPTKDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL9598196 | 0.84 | ADORA1 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9597904 | 0.83 | BPTF (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9598034 | 0.81 | PRKCI (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL618092 | 0.78 | MAPT (0.54) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL9598331 | 0.78 | ADORA1 (0.64) | MAPTKDM4EADORA1 | |
| SCHEMBL9597948 | 0.77 | RAB9A (0.55) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL9598974 | 0.74 | ADORA1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9599408 | 0.70 | KDM4E (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9603688 | 0.70 | MAPT (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013104-A1 | C.N.S. ACTIVE TRICYCLIC THIENOPYRIDINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1993-07-08 | — | — | WO | disclosed |