Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364427 | 0.79 | TSHR (0.34) | MAPTHSD17B10CA12CA1CA2 | |
| SCHEMBL2024418 | 0.74 | ALDH1A1 (0.38) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL6950110 | 0.71 | SLC7A5 (0.43) | ALOX15HSD17B10CA12CA1CA2 | |
| SCHEMBL8821951 | 0.71 | GPR119 (0.37) | TP53MAPTALOX15HSD17B10CA12 | |
| SCHEMBL1322434 | 0.71 | — | — | |
| SCHEMBL1260294 | 0.71 | — | — | |
| SCHEMBL6945827 | 0.70 | CA12 (0.35) | TP53MAPTALOX15HSD17B10CA12 | |
| SCHEMBL1299593 | 0.70 | CNR1 (0.40) | CA12CA1CA2CA9CA14 | |
| SCHEMBL17054121 | 0.70 | NR1H2 (0.37) | TP53MAPTALOX15HSD17B10CA12 | |
| SCHEMBL3903477 | 0.70 | GABRA1 (0.40) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196422-A | Antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |