SCHEMBL6364427

SCHEMBL6364427

COC(=O)c1[c]cc[c]c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
CA1 P00915 5/20 0.33
CA2 P00918 5/20 0.33
CA12 O43570 4/20 0.33
CA7 P43166 4/20 0.33
CA9 Q16790 4/20 0.33
CA14 Q9ULX7 4/20 0.33
TDP1 Q9NUW8 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 2/20 0.32
KDM4E B2RXH2 2/20 0.32
XDH P47989 2/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
NFKB1 P19838 1/20 0.32
GFER P55789 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
FUT7 Q11130 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9600314 0.79 TP53 (0.32) CA1CA2CA12CA9CA14
SCHEMBL9588234 0.79 TSHR (0.41) TSHRCA1CA2CA12CA7
SCHEMBL1322434 0.76
SCHEMBL1260294 0.75
SCHEMBL5456363 0.72 HSD17B10 (0.43) TSHRTDP1LMNAKDM4EL3MBTL1
SCHEMBL997499 0.71 MPO (0.33) TDP1LMNAKDM4EPOLBGAA
SCHEMBL51251 0.71 TSHR (0.48) TSHRCA1CA2CA12CA7
SCHEMBL7647064 0.70 TSHR (0.41) TSHRCA1CA2CA12CA7
SCHEMBL11086126 0.68 CA12 (0.47) TSHRCA1CA2CA12CA7
SCHEMBL11599488 0.68 SMN1; SMN2 (0.37) LMNAALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5561119-A ANTITUMOR AGENTS LABORATOIRES HOECHST (FR) 1996-10-01 US claimed
US-20050277751-A1 Resin and a coating solution for forming insulating film, and a method for forming an insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2005-12-15 US disclosed
US-20050025892-A1 Composition for porous organic film SUMITOMO CHEMICAL COMPANY, LIMITED 2005-02-03 US disclosed
US-20030143332-A1 Coating solution for forming insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2003-07-31 US disclosed
EP-0474227-B2 Functionalized peroxides for polymerization reactions ATOCHEM NORTH AMERICA ELF (US) 1998-06-10 EP disclosed
US-5723562-A BLOCK, GRAFT, AND CONDENSATION POLYMERIZATION; ESTERIFICATION, AMIDATION, ETHERIFICATION, CARBAMYLATION ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-03-03 US disclosed
US-5710210-A Process for polymer reactions with functionalized peroxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-01-20 US disclosed
US-5710213-A POLYMERIZING AN UNSATURATED MONOMER OR GRAFTING AN UNSATURATED POLYMER ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-01-20 US disclosed
US-5612439-A REACTING WITH MONOMERS TO FORM POLYCARBONATES, POLYESTERS, POLYAMIDES, POLYUREAS, POLYIMIDES, POLYETHERS, AND POLYURETHANES; CURING, CROSSLINKING ELF ATOCHEM NORTH AMERICA, INC. (US) 1997-03-18 US disclosed
US-5543553-A CROSSLINKING, GRAFTING AND CURING AGENTS FOR CONDENSATIONPOLYMERS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-08-06 US disclosed
US-5536790-A MOLECULAR WEIGHT CONTROL FOR POLYMERS USING PEROXY COMPOUNDS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-07-16 US disclosed
US-5534596-A CATALYSTS FOR ADDITION POLYMERIZATION, GRAFT POLYMERIZATION, CURING OF UNSATURATED POLYESTERS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-07-09 US disclosed
US-5466855-A Functionalized peroxides for polymerization reactions ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-11-14 US disclosed
US-5319130-A Monomers for condensation polymers; polyepoxides; addition polymerization initiators; compatibilizers of blends ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-06-07 US disclosed
EP-0474227-A1 Functionalized peroxides for polymerization reactions ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030143332-A1 Coating solution for forming insulating film TET1, TAS1R1, ITGA1 TSHR 4673/4885CA1 139/4885CA2 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.