SCHEMBL9601201

SCHEMBL9601201

Cc1ccc2oc(=O)sc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.57
ALOX12 P18054 7/20 0.57
ALOX15 P16050 6/20 0.57
HSD17B10 Q99714 6/20 0.57
KMT2A Q03164 5/20 0.57
ALDH1A1 P00352 5/20 0.57
HTT P42858 5/20 0.57
TDP1 Q9NUW8 5/20 0.57
PKM P14618 4/20 0.57
LMNA P02545 4/20 0.57
HPGD P15428 3/20 0.57
MEN1 O00255 2/20 0.57
POLB P06746 2/20 0.57
KDM4E B2RXH2 2/20 0.57
HSP90AA1 P07900 1/20 0.57
HSP90AB1 P08238 1/20 0.57
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
CA2 P00918 1/20 0.47
ALPI P09923 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2056163 0.84 MAOA (0.61) MAPTALOX12ALOX15HSD17B10KMT2A
SCHEMBL21063853 0.79 KMT2A (0.47) MAPTALOX12ALOX15HSD17B10KMT2A
SCHEMBL2641278 0.78 MAPT (0.48) MAPTALOX12ALOX15HSD17B10KMT2A
SCHEMBL995283 0.76 MAPT (0.47) MAPTALOX12ALOX15HSD17B10KMT2A
SCHEMBL2101251 0.76 MAPT (0.72) MAPTALOX12ALOX15HSD17B10KMT2A
SCHEMBL995285 0.76 MAPT (0.47) MAPTALOX12ALOX15HSD17B10KMT2A
SCHEMBL17368389 0.76 MAPT (0.44) MAPTALOX12ALOX15HSD17B10KMT2A
SCHEMBL2102718 0.76 ALDH1A1 (0.69) MAPTALOX12ALOX15HSD17B10KMT2A
SCHEMBL16771264 0.75 KDM4E (0.72) MAPTALOX12ALOX15HSD17B10KMT2A
SCHEMBL8035971 0.73 MAOA (0.57) MAPTALOX12ALOX15HSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5339110-A None JP disclosed
US-9488914-B2 Fluorine-containing sulfonic acid salt, fluorine-containing sulfonic acid salt resin, resist composition, and pattern forming method using same CENTRAL GLASS COMPANY, LIMITED (JP) 2016-11-08 US disclosed
US-9488914-B2 Fluorine-containing sulfonic acid salt, fluorine-containing sulfonic acid salt resin, resist composition, and pattern forming method using same CENTRAL GLASS COMPANY, LIMITED (JP) 2016-11-08 US disclosed
US-20150376120-A1 ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS Technische Universität Berlin (DE) 2015-12-31 US disclosed
US-20150198879-A1 Fluorine-Containing Sulfonic Acid Salt, Fluorine-Containing Sulfonic Acid Salt Resin, Resist Composition, and Pattern Forming Method Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2015-07-16 US disclosed
US-20150198879-A1 Fluorine-Containing Sulfonic Acid Salt, Fluorine-Containing Sulfonic Acid Salt Resin, Resist Composition, and Pattern Forming Method Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2015-07-16 US disclosed
US-8993543-B2 Diphenyl sulfide derivative and pharmaceutical product which contains same as active ingredient KYORIN PHARMACEUTICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8569270-B2 Diphenyl sulfide derivatives and medicines containing same as active ingredient KYORIN PHARMACEUTICAL CO., LTD. (JP) 2013-10-29 US disclosed
US-20130261089-A1 DIPHENYL SULFIDE DERIVATIVE AND PHARMACEUTICAL PRODUCT WHICH CONTAINS SAME AS ACTIVE INGREDIENT KYORIN PHARMACEUTICAL CO., LTD. (JP) 2013-10-03 US disclosed
WO-2013111667-A1 FLUORINE-CONTAINING SULFONIC ACID SALT, FLUORINE-CONTAINING SULFONIC ACID SALT RESIN, RESIST COMPOSITION, AND PATTERN FORMING METHOD USING SAME セントラル硝子株式会社 (JP) 2013-08-01 WO disclosed
US-20120101068-A1 DIPHENYL SULFIDE DERIVATIVES AND MEDICINES CONTAINING SAME AS ACTIVE INGREDIENT KYORIN PHARMACEUTICAL CO., LTD. (JP) 2012-04-26 US disclosed
JP-H05339110-A WATER PEST CONTROL AGENT ASAHI DENKA KOGYO KK 1993-12-21 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150376120-A1 ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS MB, ALB, BCAT2 MAPT 3111/4885ALOX12 2894/4885ALOX15 2944/4885
US-20120101068-A1 DIPHENYL SULFIDE DERIVATIVES AND MEDICINES CONTAINING SAME AS ACTIVE INGREDIENT S1PR3, S1PR1, S1PR2 MAPT 4775/4885ALOX12 720/4885ALOX15 703/4885
US-20150198879-A1 Fluorine-Containing Sulfonic Acid Salt, Fluorine-Containing Sulfonic Acid Salt Resin, Resist Composition, and Pattern Forming Method Using Same RER1, SMARCC1, SMCHD1 MAPT 3360/4885ALOX12 2696/4885ALOX15 2293/4885
US-20130261089-A1 DIPHENYL SULFIDE DERIVATIVE AND PHARMACEUTICAL PRODUCT WHICH CONTAINS SAME AS ACTIVE INGREDIENT S1PR3, S1PR1, S1PR2 MAPT 4558/4885ALOX12 427/4885ALOX15 443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.