Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602800 | 0.89 | ALDH1A1 (0.42) | POLBHTTALDH1A1PPARGPPARD | |
| SCHEMBL2162708 | 0.85 | XDH (0.39) | POLBALDH1A1PPARGPPARDPPARA | |
| SCHEMBL9603196 | 0.84 | DHFR (0.44) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL12802705 | 0.81 | ALDH1A1 (0.41) | POLBALDH1A1PPARGPPARDPPARA | |
| SCHEMBL467179 | 0.79 | GABRA1 (0.35) | POLBALDH1A1PPARGPPARDPPARA | |
| SCHEMBL9167773 | 0.79 | KDM4E (0.44) | POLBALDH1A1PPARGPPARDCYP3A4 | |
| SCHEMBL466874 | 0.78 | DHFR (0.40) | POLBALDH1A1PPARGPPARDCYP3A4 | |
| SCHEMBL112571 | 0.77 | HTT (0.52) | POLBHTTALDH1A1TP53MAPT | |
| SCHEMBL26200949 | 0.76 | ALDH1A1 (0.46) | POLBALDH1A1PPARGPPARDPPARA | |
| SCHEMBL12802185 | 0.75 | ALDH1A1 (0.48) | POLBHTTALDH1A1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198516-A | THERMALLY STABLE BISIMIDO/P-ALLYLANILINE COPOLYMERS | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |