Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601926 | 0.82 | CASP3 (0.46) | BCHEACHEGRIN1GRIN2ACASP3 | |
| SCHEMBL439684 | 0.74 | NCF1 (0.59) | BCHEACHEGRIN1GRIN2ACASP3 | |
| SCHEMBL9602321 | 0.74 | APP (0.48) | ACHEPLA2G2AKDM4E | |
| SCHEMBL12501194 | 0.73 | MPO (0.57) | BCHEACHEGRIN1GRIN2ACASP3 | |
| SCHEMBL27223540 | 0.73 | DCPS (0.53) | KDM4EMAPT | |
| SCHEMBL18980463 | 0.73 | CASP3 (0.50) | BCHEACHEGRIN1GRIN2ACASP3 | |
| SCHEMBL29722240 | 0.73 | CASP3 (0.50) | BCHEACHEGRIN1GRIN2ACASP3 | |
| SCHEMBL5045991 | 0.73 | KDM4E (0.67) | BCHEACHEGRIN1GRIN2ACASP3 | |
| SCHEMBL29594053 | 0.73 | KDM4E (0.67) | BCHEACHEGRIN1GRIN2ACASP3 | |
| SCHEMBL440157 | 0.72 | ALDH1A1 (0.64) | BCHEACHEBACE1KCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310950-B1 | Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes | RIKER LABORATORIES, INC. (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0145340-B1 | 1H-Imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1990-01-24 | — | — | EP | disclosed |
| EP-0310950-A1 | Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes | RIKER LABORATORIES, INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| US-4698348-A | 1H-imidazo[4,5-c]quinolines and their use as bronchodilating agents | RIKER LABORATORIES, INC. (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0145340-A2 | 1H-Imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1985-06-19 | — | — | EP | disclosed |