Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicyclol SCHEMBL9600725 | 0.88 | TARBP2 (0.43) | HSD17B10CYP3A4ALOX15ALDH1A1 | |
| Bicyclol SCHEMBL29380248 | 0.88 | TARBP2 (0.43) | HSD17B10CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL9601730 | 0.88 | KMT2A (0.45) | MAPTCYP3A4ALDH1A1GAAMAPK1 | |
| SCHEMBL9327972 | 0.86 | LMNA (0.42) | HSD17B10KCNK3LMNAMAPTCYP3A4 | |
| SCHEMBL9329585 | 0.84 | LMNA (0.39) | HSD17B10KCNK3LMNAMAPTCYP3A4 | |
| SCHEMBL9603034 | 0.84 | CYP3A4 (0.43) | MAPTCYP3A4ALOX15ALDH1A1 | |
| Bifendate SCHEMBL29516235 | 0.80 | TARBP2 (0.48) | HSD17B10LMNACYP3A4ALOX15ALDH1A1 | |
| Bifendate SCHEMBL30788692 | 0.80 | TARBP2 (0.48) | HSD17B10LMNACYP3A4ALOX15ALDH1A1 | |
| Bifendate SCHEMBL896166 | 0.80 | TARBP2 (0.48) | HSD17B10LMNACYP3A4ALOX15ALDH1A1 | |
| SCHEMBL23438996 | 0.79 | TARBP2 (0.41) | HSD17B10MAPTCYP3A4ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353358-B1 | BIS(METHYLENEDIOXY)BIPHENYL COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-4868207-A | Bis (methylenedioxy) biphenyl compounds useful for the treatment of liver diseases | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-09-19 | — | — | US | disclosed |