Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094972 | 0.91 | LCK (0.46) | CYP3A4ALOX15POLBLCKFYN | |
| Bicyclol SCHEMBL9600725 | 0.88 | TARBP2 (0.43) | CYP3A4ALOX15POLBALDH1A1MEN1 | |
| Bicyclol SCHEMBL29380248 | 0.88 | TARBP2 (0.43) | CYP3A4ALOX15POLBALDH1A1MEN1 | |
| SCHEMBL9602401 | 0.84 | HSD17B10 (0.40) | CYP3A4ALOX15ALDH1A1MAPT | |
| SCHEMBL9329569 | 0.83 | PKM (0.46) | CYP3A4ALOX15POLBLCKFYN | |
| SCHEMBL9328253 | 0.81 | KDM4E (0.40) | CYP3A4ALOX15POLBLCKFYN | |
| SCHEMBL9601730 | 0.80 | KMT2A (0.45) | CYP3A4ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9329600 | 0.80 | CYP3A4 (0.40) | CYP3A4ALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL1368787 | 0.78 | CYP3A4 (0.51) | CYP3A4ALOX15POLBLCKFYN | |
| Bifendate SCHEMBL29516235 | 0.78 | TARBP2 (0.48) | CYP3A4ALOX15POLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3153680-A | — | — | None | — | — | JP | disclosed |
| EP-0353358-B1 | BIS(METHYLENEDIOXY)BIPHENYL COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-08-18 | — | — | EP | disclosed |
| JP-H03153680-A | BIPHENYL COMPOUND AND PROCESS FOR PRODUCTION OF THE SAME | ZHONGGUO YIXUEKEXUEYUAN YAOWO YANJIUSUO | 1991-07-01 | — | — | JP | disclosed |
| EP-0353358-A1 | Bis(methylenedioxy)biphenyl compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-02-07 | — | — | EP | disclosed |