Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602198 | 0.92 | DRD2 (0.46) | DRD2SIRT2POLBMAPTALDH1A1 | |
| SCHEMBL9601571 | 0.84 | MEN1 (0.51) | MAPTCYP3A4CYP2C19 | |
| SCHEMBL9601933 | 0.84 | HTR3A (0.45) | — | |
| SCHEMBL7267592 | 0.83 | HTR2C (0.52) | DRD2SIRT2POLBMAPTCYP3A4 | |
| SCHEMBL9602833 | 0.83 | HTR3A (0.48) | ALDH1A1DPP4 | |
| SCHEMBL9602248 | 0.82 | MEN1 (0.43) | POLBCYP3A4ALDH1A1NPC1MAPK1 | |
| SCHEMBL9602370 | 0.78 | SMN1; SMN2 (0.48) | POLBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7267829 | 0.77 | DRD2 (0.44) | DRD2POLBNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7434439 | 0.76 | DRD2 (0.43) | DRD2POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27660153 | 0.72 | SIRT2 (0.50) | SIRT2POLBMAPTCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247266-B1 | INDOLE DERIVATIVES HAVING AN AZABICYCLIC SIDE CHAIN, PROCESS FOR THEIR PREPARATION, INTERMEDIATES, AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1993-03-10 | — | — | EP | claimed |