Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601571 | 0.87 | MEN1 (0.51) | NOTUMCHRM1MEN1KMT2ANPY5R | |
| SCHEMBL9602833 | 0.86 | HTR3A (0.48) | HTR3ANOTUMCHRM1 | |
| SCHEMBL9602598 | 0.84 | DRD2 (0.46) | — | |
| SCHEMBL9602248 | 0.84 | MEN1 (0.43) | HTR3AMEN1KMT2A | |
| SCHEMBL7265847 | 0.82 | NOTUM (0.54) | HTR3ANOTUMCHRM1CCR3BRD4 | |
| Hydrochloric Acid SCHEMBL7440870 | 0.81 | NOTUM (0.53) | HTR3ANOTUMCHRM1CCR3BRD4 | |
| SCHEMBL9602370 | 0.80 | SMN1; SMN2 (0.48) | HTR3AMEN1KMT2A | |
| SCHEMBL9602198 | 0.78 | DRD2 (0.46) | MEN1KMT2A | |
| SCHEMBL9601408 | 0.72 | SMN1; SMN2 (0.48) | NOTUMMEN1KMT2A | |
| SCHEMBL7265532 | 0.70 | NOTUM (0.56) | HTR3ANOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247266-B1 | INDOLE DERIVATIVES HAVING AN AZABICYCLIC SIDE CHAIN, PROCESS FOR THEIR PREPARATION, INTERMEDIATES, AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1993-03-10 | — | — | EP | claimed |