Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 3/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602248 | 0.95 | MEN1 (0.43) | SMN1; SMN2MEN1POLBTSHRKMT2A | |
| SCHEMBL9601408 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1POLBTSHRKMT2A | |
| SCHEMBL7266739 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1POLBTSHRKMT2A | |
| SCHEMBL9601571 | 0.80 | MEN1 (0.51) | MEN1KMT2AMAPT | |
| SCHEMBL9601933 | 0.80 | HTR3A (0.45) | MEN1KMT2AHTR3A | |
| SCHEMBL9602833 | 0.79 | HTR3A (0.48) | HTR3A | |
| SCHEMBL9602198 | 0.78 | DRD2 (0.46) | MEN1POLBKMT2AMAPT | |
| SCHEMBL9602598 | 0.78 | DRD2 (0.46) | SMN1; SMN2POLBNPC1RAB9AMAPT | |
| SCHEMBL7266518 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1POLBTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL7447009 | 0.75 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1POLBTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247266-B1 | INDOLE DERIVATIVES HAVING AN AZABICYCLIC SIDE CHAIN, PROCESS FOR THEIR PREPARATION, INTERMEDIATES, AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1993-03-10 | — | — | EP | claimed |