Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602724 | 0.84 | ALDH1A1 (0.46) | HRH3KMT2AALDH1A1GAATDP1 | |
| SCHEMBL9602082 | 0.82 | HRH3 (0.45) | HRH3KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9602093 | 0.82 | HRH3 (0.39) | HRH3KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL9601997 | 0.82 | HRH3 (0.39) | HRH3KMT2AALDH1A1GAADRD2 | |
| SCHEMBL9601550 | 0.81 | HRH3 (0.40) | HRH3KMT2AALDH1A1GAADRD2 | |
| SCHEMBL9602497 | 0.81 | ALDH1A1 (0.43) | KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9873107 | 0.80 | HRH3 (0.38) | HRH3KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL9602957 | 0.80 | PTGS1 (0.42) | KMT2ATDP1MEN1MAPT | |
| Fumaric Acid SCHEMBL9866109 | 0.80 | HRH3 (0.37) | HRH3KMT2AALDH1A1GAATDP1 | |
| Fumaric Acid SCHEMBL9602356 | 0.80 | HRH3 (0.37) | HRH3KMT2AALDH1A1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351435-B1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |