Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602780 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL9405316 | 0.80 | CA1 (0.44) | ALDH1A1CYP3A4POLBKDM4EESR1 | |
| SCHEMBL22753817 | 0.78 | SKP2 (0.55) | ALDH1A1CYP3A4TSHRTDP1POLB | |
| SCHEMBL9602783 | 0.75 | HTT (0.41) | ALDH1A1POLB | |
| SCHEMBL27964735 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL9602215 | 0.72 | GPR84 (0.33) | SKP2 | |
| SCHEMBL5610638 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL5610593 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL10046767 | 0.71 | SHBG (0.46) | ALDH1A1CYP3A4TDP1POLBKDM4E | |
| SCHEMBL17748387 | 0.71 | ESR1 (0.61) | TP53TSHRTDP1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198516-A | THERMALLY STABLE BISIMIDO/P-ALLYLANILINE COPOLYMERS | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |