Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602783 | 0.89 | HTT (0.41) | ALDH1A1HTTMAPTPOLBGAA | |
| SCHEMBL9603220 | 0.85 | ALDH1A1 (0.42) | ALDH1A1POLBSKP2KDM4ETP53 | |
| SCHEMBL10046767 | 0.81 | SHBG (0.46) | ALDH1A1HTTMAPTPOLBHPGD | |
| SCHEMBL9853387 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HTTMAPTPOLBNOS3 | |
| SCHEMBL18831681 | 0.78 | HTT (0.46) | ALDH1A1HTTMAPTPOLBNOS3 | |
| SCHEMBL29395088 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HTTMAPTPOLBNOS3 | |
| SCHEMBL48397 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HTTMAPTPOLBNOS3 | |
| SCHEMBL14068526 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HTTMAPTPOLBNOS3 | |
| SCHEMBL14213262 | 0.76 | SHBG (0.45) | DHFRCYP3A4SHBG | |
| SCHEMBL9602215 | 0.75 | GPR84 (0.33) | SKP2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198516-A | THERMALLY STABLE BISIMIDO/P-ALLYLANILINE COPOLYMERS | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |