Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602780 | 0.89 | ALDH1A1 (0.41) | HTTPOLBBACE1DHFRALDH1A1 | |
| SCHEMBL9602215 | 0.85 | GPR84 (0.33) | DHFRGPR84 | |
| SCHEMBL10046767 | 0.76 | SHBG (0.46) | HTTPOLBBACE1DHFRALDH1A1 | |
| SCHEMBL112571 | 0.75 | HTT (0.52) | HTTPOLBBACE1DHFRALDH1A1 | |
| SCHEMBL9603220 | 0.75 | ALDH1A1 (0.42) | POLBALDH1A1 | |
| SCHEMBL48459 | 0.73 | HTT (0.50) | HTTPOLBBACE1DHFRALDH1A1 | |
| SCHEMBL842010 | 0.73 | HTT (0.50) | HTTPOLBBACE1DHFRALDH1A1 | |
| SCHEMBL27954173 | 0.72 | HTT (0.48) | HTTPOLBBACE1DHFRALDH1A1 | |
| SCHEMBL11414305 | 0.71 | SKP2 (0.46) | HTTPOLBBACE1ALDH1A1GPR84 | |
| SCHEMBL14213262 | 0.71 | SHBG (0.45) | DHFRGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198516-A | THERMALLY STABLE BISIMIDO/P-ALLYLANILINE COPOLYMERS | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |