Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9599526 | 0.84 | RAB9A (0.47) | MAPTALDH1A1KDM4ENPSR1RAB9A | |
| SCHEMBL9597904 | 0.83 | BPTF (0.46) | MAPTALDH1A1TP53THRBPRKCI | |
| SCHEMBL9598196 | 0.76 | ADORA1 (0.43) | MAPTALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL9598034 | 0.72 | PRKCI (0.48) | MAPTALDH1A1PRKCIKDM4ERAB9A | |
| SCHEMBL10856568 | 0.70 | ADORA1 (0.69) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9598331 | 0.70 | ADORA1 (0.64) | MAPTPRKCIKDM4E | |
| SCHEMBL9599417 | 0.70 | KDM4E (0.57) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9603759 | 0.70 | GABRP (0.41) | MAPTALDH1A1KDM4ERAB9AHTT | |
| SCHEMBL8202194 | 0.69 | HSD17B10 (0.51) | MAPTALDH1A1TP53THRBPRKCI | |
| SCHEMBL4067002 | 0.68 | WEE1 (0.44) | MAPTALDH1A1TP53THRBPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013104-A1 | C.N.S. ACTIVE TRICYCLIC THIENOPYRIDINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1993-07-08 | — | — | WO | disclosed |