SCHEMBL9604416

SCHEMBL9604416

CCOC(=O)C(C)(O)c1ccccc1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 2/20 0.41
DRD2 P14416 1/20 0.41
MMP8 P22894 1/20 0.37
FBP1 P09467 1/20 0.37
POLB P06746 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.35
RECQL P46063 1/20 0.35
P2RY1 P47900 1/20 0.34
ABCB11 O95342 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
HTR2A P28223 1/20 0.34
PMP22 Q01453 1/20 0.34
PPARA Q07869 1/20 0.34
LMNA P02545 2/20 0.33
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8893779 0.82 PIN1 (0.38) PIN1MMP8FBP1POLBNPSR1
SCHEMBL9545821 0.81 ATM (0.37) DRD2NPSR1ALDH1A1P2RY1GAA
SCHEMBL10897157 0.75 PIN1 (0.49) PIN1MMP8POLBNPSR1TSHR
SCHEMBL8895342 0.75 TSHR (0.41) PIN1DRD2FBP1TSHRALDH1A1
SCHEMBL23218907 0.74 DRD2 (0.49) DRD2TSHRALDH1A1LMNAHPGD
SCHEMBL31355016 0.74 PIN1 (0.47) PIN1MMP8POLBNPSR1TSHR
Propionic Acid SCHEMBL29217923 0.73 L3MBTL1 (0.42) DRD2POLBNPSR1ALDH1A1RECQL
SCHEMBL29122214 0.73 TSHR (0.43) PIN1DRD2TSHRALDH1A1LMNA
SCHEMBL17389238 0.73 MAPT (0.31) DRD2NPSR1MAPT
SCHEMBL10411743 0.71 ALDH1A1 (0.49) PIN1MMP8POLBNPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993018016-A1 FUNGICIDAL OXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-16 WO disclosed