Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607483 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTLMNAL3MBTL1RAB9A | |
| SCHEMBL5630152 | 0.82 | KMT2A (0.60) | SMN1; SMN2MAPTLMNAL3MBTL1RAB9A | |
| SCHEMBL9607150 | 0.80 | MTNR1A (0.59) | LMNARAB9AHDAC1KMT2ANPC1 | |
| SCHEMBL14566276 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2MAPTLMNARAB9AALDH1A1 | |
| SCHEMBL8580572 | 0.79 | PRSS1 (0.46) | SMN1; SMN2MAPTLMNAL3MBTL1RAB9A | |
| SCHEMBL18466196 | 0.79 | ENPP2 (0.50) | MAPTLMNAKMT2AENPP2 | |
| SCHEMBL15071849 | 0.77 | ALDH1A1 (0.57) | SMN1; SMN2MAPTLMNAL3MBTL1RAB9A | |
| SCHEMBL79656 | 0.77 | CA12 (0.57) | SMN1; SMN2MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL921375 | 0.77 | ESR1 (0.64) | MAPTLMNAALDH1A1KMT2AHSD17B1 | |
| SCHEMBL70267 | 0.76 | ENPP2 (0.65) | MAPTLMNAALDH1A1KMT2AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |