Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 12/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336320 | 0.88 | TRPV4 (0.52) | TRPV4KCNH2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL29417132 | 0.88 | TRPV4 (0.52) | TRPV4KCNH2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL18003021 | 0.85 | KIF11 (0.47) | TRPV4TRPV3KCNH2 | |
| SCHEMBL2271123 | 0.82 | KDM1A (0.49) | CYP11B1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL28682644 | 0.79 | CYP11B1 (0.56) | CYP11B1ALDH1A1L3MBTL1 | |
| SCHEMBL30747787 | 0.79 | CYP11B1 (0.56) | CYP11B1ALDH1A1L3MBTL1 | |
| SCHEMBL10325176 | 0.78 | CYP11B1 (0.43) | CYP11B1ALDH1A1L3MBTL1 | |
| SCHEMBL19807802 | 0.77 | PIK3CA (0.43) | TRPV3KCNH2 | |
| SCHEMBL25212518 | 0.77 | TRPV4 (0.44) | DGAT1TRPV4TRPV3KCNH2 | |
| SCHEMBL4425760 | 0.76 | ALDH1A1 (0.54) | CYP11B1KCNH2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |