Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366445 | 0.84 | PDE2A (0.44) | ALDH1A1 | |
| SCHEMBL31556432 | 0.81 | EPHX2 (0.38) | — | |
| SCHEMBL13580965 | 0.81 | KIF11 (0.44) | CHRM5 | |
| SCHEMBL12952645 | 0.81 | EPHX2 (0.38) | — | |
| SCHEMBL18003308 | 0.80 | SRD5A2 (0.44) | DAOCHRM5POLBMAPT | |
| SCHEMBL2092054 | 0.78 | SLC6A4 (0.56) | DAOSLC6A4GPR84CHRM5MPO | |
| SCHEMBL9607433 | 0.77 | ALDH1A1 (0.49) | DAOSLC6A4GPR84ALDH1A1TSHR | |
| SCHEMBL25949721 | 0.77 | CALM1 (0.44) | MPO | |
| SCHEMBL38652385 | 0.76 | RAB9A (0.46) | DAOSLC6A4GPR84CHRM5MPO | |
| SCHEMBL9607326 | 0.76 | MAOA (0.44) | DAOSLC6A4GPR84CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |