Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536085 | 0.85 | ACP1 (0.47) | LMNAMAPTKDM4EALDH1A1PKM | |
| SCHEMBL6001382 | 0.78 | CYP19A1 (0.60) | LMNAKDM4EALDH1A1L3MBTL1CYP19A1 | |
| SCHEMBL20010448 | 0.75 | FGFR3 (0.52) | LMNAMAPTKDM4EALDH1A1PKM | |
| SCHEMBL8655903 | 0.74 | LMNA (0.44) | LMNAMAPTALDH1A1L3MBTL1CREBBP | |
| SCHEMBL9607232 | 0.72 | ABL1 (0.42) | LMNAMAPTKDM4EALDH1A1PGK1 | |
| SCHEMBL19989137 | 0.71 | KDM4E (0.40) | LMNAMAPTKDM4EALDH1A1PKM | |
| SCHEMBL3457404 | 0.71 | PLA2G2A (0.46) | LMNAMAPTALDH1A1CYP19A1ACP1 | |
| SCHEMBL29793367 | 0.70 | ACHE (0.61) | LMNAKDM4EALDH1A1L3MBTL1ADORA1 | |
| SCHEMBL785473 | 0.70 | ACHE (0.61) | LMNAKDM4EALDH1A1L3MBTL1ADORA1 | |
| SCHEMBL4182669 | 0.70 | PGK1 (0.51) | L3MBTL1CREBBPPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |