Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536085 | 0.87 | ACP1 (0.47) | ABL1BCRKLKB1KCNH2MAPT | |
| SCHEMBL8534140 | 0.74 | ALDH1A1 (0.45) | KLKB1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL18097397 | 0.73 | PDE2A (0.47) | ABL1BCRKLKB1KCNH2CHRM5 | |
| SCHEMBL8538579 | 0.73 | MAT2A (0.61) | ABL1BCRKLKB1KCNH2CHRM5 | |
| SCHEMBL9607518 | 0.72 | LMNA (0.47) | MAPTKDM4EALDH1A1LMNAPGK1 | |
| SCHEMBL5480798 | 0.71 | PDE10A (0.48) | KCNH2NTRK1CSF1RNTRK2 | |
| SCHEMBL24930970 | 0.71 | CSNK2A1 (0.41) | KLKB1KCNH2MAPTGRM2KDM4E | |
| SCHEMBL30239845 | 0.71 | CSNK2A1 (0.41) | KLKB1KCNH2MAPTGRM2KDM4E | |
| SCHEMBL6534170 | 0.71 | KDM4E (0.58) | CYP3A4MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL9607226 | 0.70 | TRPM8 (0.44) | ABL1BCRKLKB1KCNH2PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |