SCHEMBL9607520

SCHEMBL9607520

CCOC(C)Oc1ccc(C(=CC=C(c2ccc(C)cc2)c2ccc(C)cc2)c2ccc(OC(C)OCC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.43
PPARD Q03181 3/20 0.43
PPARA Q07869 3/20 0.43
MAPT P10636 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KMT2A Q03164 4/20 0.38
MEN1 O00255 2/20 0.38
MAOB P27338 1/20 0.37
ALDH1A1 P00352 2/20 0.34
POLB P06746 2/20 0.34
LMNA P02545 2/20 0.34
NLRP1 Q9C000 1/20 0.34
FFAR1 O14842 1/20 0.33
SCN5A Q14524 1/20 0.33
SCN2A Q99250 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33
PARP10 Q53GL7 1/20 0.33
TP53 P04637 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14009524 0.85 LMNA (0.44) PPARGPPARAMAPTNPSR1KMT2A
SCHEMBL279491 0.83 CNR2 (0.36) MAPTKMT2AMEN1ALDH1A1POLB
SCHEMBL3852488 0.78 LMNA (0.52) PPARAKMT2APOLBLMNAPARP10
SCHEMBL685750 0.78 KMT2A (0.37) PPARGPPARAMAPTNPSR1KMT2A
SCHEMBL9607521 0.75 TDP1 (0.49) PPARGPPARDPPARAMAPTKMT2A
SCHEMBL11145345 0.74 KMT2A (0.62) MAPTKMT2AALDH1A1HTTPARP10
SCHEMBL810801 0.74 MAPT (0.50) PPARGPPARAMAPTNPSR1KMT2A
SCHEMBL13845305 0.74 FFAR1 (0.54) PPARGPPARDPPARAMAPTMAOB
SCHEMBL5963165 0.73 LTA4H (0.47) MAPTKMT2AMEN1LMNATDP1
Hydrochloric Acid SCHEMBL11155443 0.73 KMT2A (0.61) MAPTKMT2AALDH1A1HTTPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed