SCHEMBL9607521

SCHEMBL9607521

CCOC(C)OC(=O)Cc1ccc(C(=CC=C(c2ccc(C)cc2)c2ccc(C)cc2)c2ccc(CC(=O)OC(C)OCC)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.49
PPARG P37231 3/20 0.46
PPARD Q03181 3/20 0.46
PPARA Q07869 3/20 0.46
KMT2A Q03164 2/20 0.39
TSHR P16473 1/20 0.39
L3MBTL1 Q9Y468 4/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MAPT P10636 1/20 0.38
LMNA P02545 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279172 0.85 MEN1 (0.40) TDP1KMT2ATSHRL3MBTL1MAPT
SCHEMBL28389293 0.76 TSHR (0.67) TSHRL3MBTL1NPC1RAB9AALDH1A1
SCHEMBL9607520 0.75 PPARG (0.43) TDP1PPARGPPARDPPARAKMT2A
SCHEMBL24600114 0.74 L3MBTL1 (0.49) TDP1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL10309729 0.72 TSHR (0.70) TDP1KMT2ATSHRL3MBTL1NPC1
SCHEMBL279567 0.72 TSHR (0.53) PPARGPPARAKMT2ATSHRL3MBTL1
SCHEMBL1107146 0.69 CYP4Z1 (0.57) KMT2ATSHRL3MBTL1MAPTLMNA
SCHEMBL11210304 0.68 TDP1 (0.54) TDP1KMT2ATSHRL3MBTL1NPC1
SCHEMBL10196961 0.68 HPGD (0.46) TDP1PPARGPPARDPPARAKMT2A
SCHEMBL9607510 0.68 MGLL (0.57) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed