Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 3/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10278344 | 1.00 | SCN9A (0.33) | SCN9AGSK3BDYRK1AAAK1ABL1 | |
| SCHEMBL9607998 | 0.94 | SCN9A (0.33) | SCN9AGSK3BDYRK1AAAK1ABL1 | |
| SCHEMBL2724552 | 0.94 | SCN9A (0.32) | SCN9AGSK3BDYRK1AAAK1PTPN1 | |
| SCHEMBL212278 | 0.94 | SCN9A (0.32) | SCN9AGSK3BDYRK1AAAK1PTPN1 | |
| SCHEMBL14734323 | 0.92 | SCN9A (0.32) | SCN9AGSK3BDYRK1AAAK1 | |
| SCHEMBL211004 | 0.87 | SCN9A (0.33) | SCN9AGSK3BDYRK1AAAK1PTPN1 | |
| SCHEMBL14734306 | 0.86 | SCN9A (0.32) | SCN9AGSK3BDYRK1APTPN1CTSS | |
| SCHEMBL9607846 | 0.86 | ABL1 (0.35) | GSK3BDYRK1AABL1 | |
| SCHEMBL10278364 | 0.84 | ABL1 (0.34) | ABL1 | |
| SCHEMBL212277 | 0.83 | CDK9 (0.32) | SCN9AGSK3BDYRK1ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | SCN9A 2543/4885GSK3B 776/4885DYRK1A 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.