Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734323 | 0.94 | SCN9A (0.32) | SCN9AGSK3BDYRK1ACDK9 | |
| SCHEMBL9607998 | 0.92 | SCN9A (0.33) | SCN9AGSK3BDYRK1APTPN1CTSS | |
| SCHEMBL211004 | 0.92 | SCN9A (0.33) | SCN9AGSK3BDYRK1ACDK9PTPN1 | |
| SCHEMBL14734336 | 0.88 | GSK3B (0.33) | GSK3BDYRK1ACDK9 | |
| SCHEMBL9608028 | 0.86 | SCN9A (0.33) | SCN9AGSK3BDYRK1APTPN1CTSS | |
| SCHEMBL10278344 | 0.86 | SCN9A (0.33) | SCN9AGSK3BDYRK1APTPN1CTSS | |
| SCHEMBL2724552 | 0.86 | SCN9A (0.32) | SCN9AGSK3BDYRK1ACDK9PTPN1 | |
| SCHEMBL212278 | 0.86 | SCN9A (0.32) | SCN9AGSK3BDYRK1ACDK9PTPN1 | |
| SCHEMBL14734322 | 0.84 | CARM1 (0.36) | — | |
| SCHEMBL211003 | 0.82 | CDK9 (0.32) | SCN9AGSK3BDYRK1ACDK9PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053348-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053348-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | SCN9A 2543/4885GSK3B 776/4885DYRK1A 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.