Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17922506 | 0.86 | P2RX7 (0.54) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL2047977 | 0.86 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL9608983 | 0.84 | MAPT (0.47) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL13957778 | 0.84 | SMN1; SMN2 (0.55) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL3902799 | 0.84 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL25440035 | 0.83 | MAPT (0.62) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL26331616 | 0.83 | SMN1; SMN2 (0.51) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL31584200 | 0.81 | ALDH1A1 (0.56) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL6527813 | 0.80 | ALDH1A1 (0.52) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL14310927 | 0.79 | MAPT (0.74) | MAPTSMN1; SMN2POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200115356-A1 | Modulation of Bacterial Quorum Sensing With Synthetic Ligands | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2020-04-16 | — | — | US | disclosed |
| US-20120135975-A1 | Substituted Esters as Cannabinoid-1 Receptor Modulators | MERCK & CO., INC. (US) | 2012-05-31 | — | — | US | disclosed |
| US-7932283-B2 | Fungicide N-cyclopropyl-sulfonylamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| EP-1414809-B1 | INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION | BAYER CORP (US) | 2008-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312435-A1 | Imine Compound | CNR1, CNR2, HRH4 | MAPT 4160/4885SMN1; SMN2 1844/4885POLB 4390/4885 |
| US-20200115356-A1 | Modulation of Bacterial Quorum Sensing With Synthetic Ligands | AHCYL1, EBPL, AIP | MAPT 4822/4885SMN1; SMN2 4883/4885POLB 4816/4885 |
| US-20120135975-A1 | Substituted Esters as Cannabinoid-1 Receptor Modulators | CNR1, CNR2, FAAH | MAPT 764/4885SMN1; SMN2 398/4885POLB 2185/4885 |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | CYP51A1, ERG28, CBR3 | MAPT 2939/4885SMN1; SMN2 2319/4885POLB 4713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.