Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762944 | 0.84 | HRH4 (0.49) | SHMT2TERTCCNA2CDK2CHRM2 | |
| SCHEMBL25783078 | 0.79 | BRAF (0.47) | SHMT2TERTCCNA2CDK2NOS1 | |
| SCHEMBL25588056 | 0.77 | SHMT2 (0.53) | SHMT2ECE2NPC1RAB9A | |
| SCHEMBL25584926 | 0.76 | SHMT2 (0.49) | SHMT2NOS1ECE2NPC1RAB9A | |
| SCHEMBL9609741 | 0.76 | SHMT2 (0.39) | SHMT2 | |
| SCHEMBL7981962 | 0.74 | LOXL2 (0.47) | CHRM2ROCK1ROCK2KCNH2 | |
| SCHEMBL9611256 | 0.74 | ECE2 (0.36) | SHMT2ECE2NPC1RAB9A | |
| SCHEMBL5547086 | 0.72 | SHMT2 (0.51) | SHMT2ECE2NPC1RAB9A | |
| SCHEMBL16585598 | 0.72 | SHMT2 (0.51) | SHMT2NOS1ECE2NPC1RAB9A | |
| SCHEMBL7992413 | 0.72 | ALDH1A1 (0.56) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135651-A1 | Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen | VENTANA RESEARCH CORPORATION | 2012-05-31 | — | — | US | disclosed |