Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL1357275 | 0.94 | HDAC1 (0.38) | ADRB2CYP2A6CA2PTGDR2OGG1 | |
| Fumaric Acid SCHEMBL1357277 | 0.94 | HDAC1 (0.38) | ADRB2CYP2A6CA2PTGDR2OGG1 | |
| SCHEMBL1156110 | 0.79 | ADRB2 (0.42) | ADRB2CYP2A6CA2PTGDR2KIT | |
| Hydrochloric Acid SCHEMBL1156645 | 0.78 | ADRB2 (0.41) | ADRB2CYP2A6CA2PTGDR2KIT | |
| SCHEMBL1358382 | 0.77 | RAPGEF4 (0.45) | OGG1SMN1; SMN2LMNAHTT | |
| SCHEMBL1357890 | 0.77 | NR1H2 (0.48) | SMN1; SMN2LMNATSHRHTT | |
| Fumaric Acid SCHEMBL1357693 | 0.76 | RAB9A (0.39) | SMN1; SMN2LMNATSHRHTT | |
| Fumaric Acid SCHEMBL1357695 | 0.76 | RAB9A (0.39) | SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL9611258 | 0.75 | SMN1; SMN2 (0.39) | PTGDR2OGG1SMN1; SMN2HSD17B10LMNA | |
| SCHEMBL12136107 | 0.73 | MAPT (0.41) | LMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2005957-B1 | ACID SECRETION INHIBITOR | TAKEDA PHARMACEUTICAL (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-20110288040-A1 | ARYL- OR HETEROARYL-SULFONYL COMPOUNDS AS ACID SECRETION INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110288040-A1 | ARYL- OR HETEROARYL-SULFONYL COMPOUNDS AS ACID SECRETION INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-24 | — | — | US | disclosed |
| US-7994205-B2 | Aryl-or heteroaryl-sulfonyl compounds as acid secretion inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7994205-B2 | Aryl-or heteroaryl-sulfonyl compounds as acid secretion inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20090118335-A1 | Acid Secretion Inhibitor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20090118335-A1 | Acid Secretion Inhibitor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118335-A1 | Acid Secretion Inhibitor | ATP6AP1, HRH2, ATP6V1G1 | ADRB2 2041/4885CYP2A6 35/4885CA2 21/4885 |
| US-20110288040-A1 | ARYL- OR HETEROARYL-SULFONYL COMPOUNDS AS ACID SECRETION INHIBITORS | GHSR, GIPR, HRH2 | ADRB2 1277/4885CYP2A6 39/4885CA2 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.