Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372519 | 0.98 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Iodide SCHEMBL1758290 | 0.96 | SMN1; SMN2 (0.41) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Bromide SCHEMBL5168946 | 0.96 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Fluoride Ion SCHEMBL5172541 | 0.96 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2HSP90AA1FDPS | |
| Hydrochloric Acid SCHEMBL962124 | 0.94 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2HSP90AA1MAPT | |
| Hydrochloric Acid SCHEMBL25413444 | 0.92 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2HSP90AA1MAPT | |
| Hydrochloric Acid SCHEMBL25415803 | 0.92 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2HSP90AA1MAPT | |
| Hydrochloric Acid SCHEMBL22026956 | 0.92 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2HSP90AA1MAPT | |
| Hydrochloric Acid SCHEMBL25415755 | 0.92 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2HSP90AA1MAPT | |
| Hydrochloric Acid SCHEMBL960532 | 0.92 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2HSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651114-B | Method for synthesizing alkyl aromatic aldehyde | 中国石油化工股份有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-109647528-B | Catalyst for synthesizing alkyl aromatic aldehyde | 中国石油化工股份有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-109651112-B | Method for synthesizing alkyl aromatic aldehyde by alkyl aromatic hydrocarbon carbonylation | 中国石油化工股份有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-107847867-B | Composite membranes having improved performance and/or durability and methods of use thereof | 3M创新有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-108409581-B | Preparation method of dinonyl-substituted diphenylamine antioxidant | 江苏飞亚化学工业有限责任公司 | 2020-07-14 | — | — | CN | claimed |
| US-20200164319-A1 | COMPOSITE MEMBRANES WITH IMPROVED PERFORMANCE AND/OR DURABILITY AND METHODS OF USE | 3M INNOVATIVE PROPERTIES COMPANY | 2020-05-28 | — | — | US | claimed |
| US-20200030748-A1 | COMPOSITE MEMBRANES WITH IMPROVED PERFORMANCE AND/OR DURABILITY AND METHODS OF USE | 3M INNOVATIVE PROPERTIES COMPANY | 2020-01-30 | — | — | US | claimed |
| CN-110665017-A | Preparation method of sensitizer for targeting tumor to combine CT imaging and photothermal therapy | 上海纳米技术及应用国家工程研究中心有限公司 | 2020-01-10 | — | — | CN | claimed |
| CN-110559439-A | Preparation method of photo-thermal and photodynamic cooperative therapeutic agent | 上海纳米技术及应用国家工程研究中心有限公司 | 2019-12-13 | — | — | CN | claimed |
| US-10478778-B2 | Composite membranes with improved performance and/or durability and methods of use | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-11-19 | — | — | US | claimed |
| US-20120207525-A1 | RESISTANCE HEATING COMPOSITION AND HEATING COMPOSITE, HEATING APPARATUS, AND FUSING APPARATUS, INCLUDING RESISTANCE HEATING COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2012-08-16 | — | — | US | claimed |
| US-7943543-B1 | Ionic liquid-solid-polymer mixed matrix membranes for gas separations | UOP LLC (US) | 2011-05-17 | — | — | US | claimed |
| US-20110000782-A1 | ALUMINUM RECOVERY PROCESS | THE UNIVERSITY OF ALABAMA (US) | 2011-01-06 | — | — | US | claimed |
| WO-2009102419-A2 | ALUMINUM RECOVERY PROCESS | THE UNIVERSITY OF ALABAMA (US) | 2009-08-20 | — | — | WO | claimed |
| EP-1663921-B1 | METHOD FOR PRODUCING HALOALKANES FROM ALCOHOLS | BASF AG (DE) | 2007-05-02 | — | — | EP | claimed |
| US-20070055084-A1 | Method for producing haloalkanes from alcohols | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-08 | — | — | US | claimed |
| WO-2003051894-A1 | PREPARATION OF IONIC LIQUIDS | CYTEC CANADA INC. (CA) | 2003-06-26 | — | — | WO | claimed |
| US-6579343-B2 | Contacting gas with a liquid ionic compound comprising a nitrogen-containing heterocyclic cation | UNIVERSITY OF NOTRE DAME DU LAC | 2003-06-17 | — | — | US | claimed |
| US-20020189444-A1 | Purification of gas with liquid ionic compounds | NATIONAL SCIENCE FOUNDATION | 2002-12-19 | — | — | US | claimed |
| EP-0693045-B1 | ALKYLATION PROCESS | BP CHEM INT LTD (GB) | 1997-10-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070055084-A1 | Method for producing haloalkanes from alcohols | ADH1C, HDHD5, ADH5 | MEN1 4351/4885KMT2A 735/4885SMN1; SMN2 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.