Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9610829 | 0.92 | ALDH1A1 (0.57) | ALDH1A1LTA4HGAATHRBSMN1; SMN2 | |
| SCHEMBL4424464 | 0.92 | ALDH1A1 (0.57) | ALDH1A1LTA4HGAATHRBSMN1; SMN2 | |
| SCHEMBL15694240 | 0.86 | GAA (0.51) | ALDH1A1LTA4HGAATHRBSMN1; SMN2 | |
| SCHEMBL21043978 | 0.84 | SIGMAR1 (0.53) | ALDH1A1LTA4HGAATHRBSMN1; SMN2 | |
| SCHEMBL10074441 | 0.84 | HDAC1 (0.62) | ALDH1A1LTA4HGAATHRBSMN1; SMN2 | |
| SCHEMBL29299520 | 0.83 | HRH3 (0.51) | ALDH1A1SMN1; SMN2LMNAHRH3KDM4E | |
| SCHEMBL13673397 | 0.82 | LTA4H (0.48) | ALDH1A1LTA4HGAATHRBSMN1; SMN2 | |
| SCHEMBL14997825 | 0.81 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2LMNAMAPTCYP3A4 | |
| SCHEMBL18292042 | 0.80 | KDM4E (0.63) | ALDH1A1SMN1; SMN2HRH3KDM4EMEN1 | |
| SCHEMBL22361385 | 0.80 | KDM4E (0.63) | ALDH1A1SMN1; SMN2HRH3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | ALDH1A1 4559/4885LTA4H 4557/4885GAA 654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.