SCHEMBL4424464

SCHEMBL4424464

O=C(O)CN1CCN(CC(=O)O)CCN(Cc2ccc(C(=O)O)cc2)CCN(CC(=O)O)CC1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
LTA4H P09960 3/20 0.55
HDAC1 Q13547 2/20 0.54
HDAC4 P56524 1/20 0.54
KCNH2 Q12809 1/20 0.54
MAPT P10636 2/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
MAPK1 P28482 1/20 0.54
CYP2C19 P33261 1/20 0.54
GAA P10253 2/20 0.52
THRB P10828 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 1/20 0.52
KDM1A O60341 3/20 0.50
HDAC6 Q9UBN7 2/20 0.49
HDAC8 Q9BY41 1/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
USP2 O75604 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9610829 1.00 ALDH1A1 (0.57) ALDH1A1LTA4HHDAC1HDAC4KCNH2
SCHEMBL9612243 0.92 ALDH1A1 (0.50) ALDH1A1LTA4HHDAC1HDAC4KCNH2
SCHEMBL21043978 0.91 SIGMAR1 (0.53) ALDH1A1LTA4HHDAC1HDAC4KCNH2
SCHEMBL10074441 0.91 HDAC1 (0.62) ALDH1A1LTA4HHDAC1HDAC4KCNH2
SCHEMBL15694240 0.90 GAA (0.51) ALDH1A1LTA4HHDAC1HDAC4KCNH2
SCHEMBL13673397 0.86 LTA4H (0.48) ALDH1A1LTA4HHDAC1HDAC4KCNH2
SCHEMBL27519383 0.86 HDAC4 (0.71) ALDH1A1LTA4HHDAC1HDAC4KCNH2
SCHEMBL17029298 0.85 ALDH1A1 (0.53) ALDH1A1LTA4HHDAC1HDAC4KCNH2
SCHEMBL8510915 0.84 ITGB3 (0.56) ALDH1A1HDAC1HDAC4KCNH2MAPT
SCHEMBL9610969 0.84 ALDH1A1 (0.54) ALDH1A1HDAC1HDAC4KCNH2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511728-B Compound for separating rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2023-12-08 CN claimed
US-20230227942-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE TECHNOLOGIES, LLC 2023-07-20 US claimed
CN-115836137-A Separation of rare earth elements 阳光科技公司 2023-03-21 CN claimed
EP-4127255-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE Technologies, LLC (US) 2023-02-08 EP claimed
EP-3717466-B1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2022-01-05 EP claimed
WO-2021202914-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE Medical Technologies, LLC (US) 2021-10-07 WO claimed
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2020-09-10 US claimed
EP-3492460-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS, METHOD OF SEPARATION, AND USE THEREOF Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) 2019-06-05 EP claimed
EP-1434768-B1 ENHANCED SUBSTRATE IMAGING BY REVERSIBLE BINDING TO A PARAMAGNETIC COMPLEX BRACCO IMAGING SPA (IT) 2009-08-12 EP claimed
US-20040258618-A1 Enhanced substrate imaging by reversible binding to a paramagnetic complex BRACCO IMAGING S.P.A. (IT) 2004-12-23 US claimed
US-20250229198-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I (CZ) 2025-07-17 US disclosed
US-12268977-B2 Compounds for separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR. V.V.I. (CZ) 2025-04-08 US disclosed
CN-111511728-B Compound for separating rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2023-12-08 CN disclosed
US-20230227942-A1 SEPARATION OF RARE EARTH ELEMENTS SHINE TECHNOLOGIES, LLC 2023-07-20 US disclosed
CN-115836137-A Separation of rare earth elements 阳光科技公司 2023-03-21 CN disclosed
US-7608249-B2 Enhanced substrate imaging by reversible binding to a paramagnetic complex BRACCO IMAGING S.P.A. (IT) 2009-10-27 US disclosed
EP-1434768-B1 ENHANCED SUBSTRATE IMAGING BY REVERSIBLE BINDING TO A PARAMAGNETIC COMPLEX BRACCO IMAGING SPA (IT) 2009-08-12 EP disclosed
US-20040258618-A1 Enhanced substrate imaging by reversible binding to a paramagnetic complex BRACCO IMAGING S.P.A. (IT) 2004-12-23 US disclosed
EP-1434768-A1 ENHANCED SUBSTRATE IMAGING BY REVERSIBLE BINDING TO A PARAMAGNETIC COMPLEX Bracco Imaging S.p.A. (IT) 2004-07-07 EP disclosed
WO-2003033479-A1 ENHANCED SUBSTRATE IMAGING BY REVERSIBLE BINDING TO A PARAMAGNETIC COMPLEX BRACCO IMAGING S.P.A. (IT) 2003-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250229198-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF SCO2, SOD3, SLC39A3 ALDH1A1 4085/4885LTA4H 3801/4885HDAC1 1896/4885
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF SCLY, SFXN1, PTCD3 ALDH1A1 2634/4885LTA4H 4272/4885HDAC1 3383/4885
US-12268977-B2 Compounds for separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof SCLY, SFXN1, PTCD3 ALDH1A1 2634/4885LTA4H 4272/4885HDAC1 3383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.