SCHEMBL18174769

SCHEMBL18174769

Cc1cncc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccc(C)nc5)c5ccccc45)c4ccccc34)cc2)c1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.36
CYP2A6 P11509 3/20 0.35
TDO2 P48775 2/20 0.35
CDK7 P50613 1/20 0.35
COMT P21964 1/20 0.35
CYP11B2 P19099 2/20 0.34
CYP11B1 P15538 2/20 0.34
PDE10A Q9Y233 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
MAPK10 P53779 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
PSMB5 P28074 1/20 0.33
PTGS2 P35354 2/20 0.33
MAPK1 P28482 1/20 0.32
NPC1 O15118 1/20 0.32
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174766 0.95 TDO2 (0.37) PDK2CYP2A6TDO2COMTCYP11B2
SCHEMBL18174698 0.91 GPR55 (0.40) PDK2CYP2A6TDO2CDK7CYP11B2
SCHEMBL18174764 0.89 CYP2A6 (0.41) CYP2A6TDO2CDK7CYP11B2CYP11B1
SCHEMBL15161110 0.88 CYP11B1 (0.44) CYP2A6CYP11B2CYP11B1MAPK10PTGS2
SCHEMBL9612943 0.87 CYP2A6 (0.39) CYP2A6TDO2CDK7COMTCYP11B2
SCHEMBL18174772 0.86 PDK2 (0.42) PDK2TDO2COMTPDE10AMAPK10
SCHEMBL18174790 0.85 WNT3A (0.42) PDK2CYP2A6TDO2PDE10A
SCHEMBL15161071 0.85 CYP11B2 (0.37) CYP2A6CDK7CYP11B2CYP11B1GPR55
SCHEMBL15161048 0.85 CYP11B2 (0.37) CYP2A6CDK7CYP11B2CYP11B1GPR55
SCHEMBL18174777 0.84 CYP2A6 (0.40) CYP2A6CDK7CYP11B2CYP11B1MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed