Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596652 | 0.85 | HTR1A (0.52) | HTR2AMAPTMEN1KMT2ALMNA | |
| SCHEMBL9228149 | 0.82 | HTR1A (0.50) | HTR2AMAPTMEN1KMT2ALMNA | |
| SCHEMBL10554214 | 0.76 | HTR1A (0.70) | HTR2AHTR1A | |
| SCHEMBL4106853 | 0.76 | HTR2A (0.77) | HTR2AMTNR1AHTR1AMPO | |
| SCHEMBL9513567 | 0.76 | HTR1A (0.46) | HTR2AMAPTMEN1KMT2ALMNA | |
| SCHEMBL10554132 | 0.75 | DRD2 (0.59) | HTR2AHTR1AHTR2B | |
| SCHEMBL9514753 | 0.75 | HTR1A (0.45) | HTR2AMAPTMEN1KMT2ALMNA | |
| SCHEMBL6948769 | 0.74 | HTR2A (0.67) | HTR2AMAPTMEN1KMT2ALMNA | |
| SCHEMBL10278413 | 0.74 | HTR2A (0.68) | HTR2AMAPTMEN1KMT2AMTNR1A | |
| SCHEMBL18409742 | 0.74 | HTR2A (0.76) | HTR2AMAPTMEN1KMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515462-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991012252-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-08-22 | — | — | WO | disclosed |