Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6683793 | 0.99 | MAPT (0.36) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL6535868 | 0.95 | LMNA (0.38) | MAPTALDH1A1KDM4EHPGDGAA | |
| Sulfuric Acid SCHEMBL10955650 | 0.84 | KDM4E (0.38) | MAPTALDH1A1KDM4EHPGDGAA | |
| Sulfuric Acid SCHEMBL8777212 | 0.83 | HCAR3 (0.31) | — | |
| Sulfuric Acid SCHEMBL6550045 | 0.83 | KDM4E (0.39) | MAPTALDH1A1KDM4EHPGDGAA | |
| Water SCHEMBL9303938 | 0.81 | ALDH1A1 (0.32) | MAPTALDH1A1KDM4EHPGDNQO2 | |
| SCHEMBL6565570 | 0.79 | POLB (0.41) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL9443960 | 0.79 | S100B (0.34) | — | |
| SCHEMBL8036530 | 0.75 | KDM4E (0.41) | MAPTALDH1A1KDM4EHPGDGAA | |
| Sulfuric Acid SCHEMBL6550837 | 0.75 | ALDH1A1 (0.35) | MAPTALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486629-A1 | SILVER HALIDE GRAINS HAVING SMALL TWIN-PLANE SEPARATIONS. | EASTMAN KODAK CO (US) | 1992-05-27 | — | — | EP | disclosed |
| WO-1991018320-A1 | SILVER HALIDE GRAINS HAVING SMALL TWIN-PLANE SEPARATIONS | EASTMAN KODAK COMPANY (US) | 1991-11-28 | — | — | WO | disclosed |
| EP-0426805-A1 | PHOTOGRAPHIC BETA-KETOAMIDE AND PHOTOGRAPHIC ELEMENTS CONTAINING THEM. | KODAK LTD (GB) | 1991-05-15 | — | — | EP | disclosed |
| WO-1990013852-A1 | PHOTOGRAPHIC BETA-KETOAMIDE AND PHOTOGRAPHIC ELEMENTS CONTAINING THEM | EASTMAN KODAK COMPANY (US) | 1990-11-15 | — | — | WO | disclosed |