Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FGB | P02675 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768344 | 0.82 | KDM4E (0.42) | ALDH1A1MAPTLMNASMN1; SMN2HIF1A | |
| SCHEMBL28628608 | 0.79 | LMNA (0.30) | LMNASMN1; SMN2HIF1A | |
| SCHEMBL9385400 | 0.69 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL25430666 | 0.69 | MAPT (0.46) | ALDH1A1MAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL29440753 | 0.68 | TDP2 (0.38) | ALDH1A1MAPTLMNAKDM4ECYP1A2 | |
| SCHEMBL9615419 | 0.67 | NPSR1 (0.44) | ALDH1A1MAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL28023074 | 0.66 | MAPT (0.33) | ALDH1A1MAPTLMNATSHRKDM4E | |
| SCHEMBL28560072 | 0.66 | KDM4E (0.40) | ALDH1A1MAPTSMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL29440764 | 0.66 | KDM4E (0.40) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2649630 | 0.65 | TDP1 (0.42) | ALDH1A1MAPTLMNASMN1; SMN2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402459-A | Method and device for synthesizing 4-hydroxyquinoline-3-formic acid | 贵州中医药大学 | 2021-09-17 | — | — | CN | disclosed |