Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18118615 | 0.84 | BCL2 (0.57) | BCL2MCL1BCL2L1ALDH1A1GAA | |
| SCHEMBL7291911 | 0.77 | ALOX15 (0.37) | ALDH1A1GAAPKMALOX15NPSR1 | |
| SCHEMBL7295669 | 0.77 | ROCK2 (0.41) | ALDH1A1PKMALOX15POLB | |
| SCHEMBL7302874 | 0.77 | ROCK2 (0.41) | ALDH1A1PKMALOX15POLB | |
| SCHEMBL6690700 | 0.77 | HIF1A (0.60) | ALDH1A1GAAPKMPOLB | |
| SCHEMBL7303150 | 0.74 | ALDH1A1 (0.38) | ALDH1A1PKMALOX15POLB | |
| SCHEMBL3085221 | 0.72 | ALDH1A1 (0.52) | ALDH1A1GAAPKMHDAC1HDAC6 | |
| SCHEMBL9665668 | 0.72 | HRH3 (0.45) | GAAPLA2G10PLA2G5POLB | |
| SCHEMBL9479076 | 0.72 | HRH3 (0.45) | GAAPLA2G10PLA2G5POLB | |
| SCHEMBL9666858 | 0.72 | HRH3 (0.45) | GAAPLA2G10PLA2G5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4164071-A | — | — | None | — | — | JP | disclosed |
| JP-H04164071-A | HYDANTOIN DERIVATIVE AND PRODUCTION THEREOF | SUMITOMO CHEM CO LTD | 1992-06-09 | — | — | JP | disclosed |