Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TGM2 | P21980 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685622 | 0.96 | TSHR (0.48) | TSHRTGM2ACACBALDH1A1MAPK1 | |
| SCHEMBL36064 | 0.81 | TSHR (0.52) | TSHRTGM2ACACBALDH1A1MAPK1 | |
| SCHEMBL28750633 | 0.81 | TSHR (0.52) | TSHRTGM2ACACBALDH1A1MAPK1 | |
| SCHEMBL7211824 | 0.81 | ACACB (0.36) | TSHRACACBALDH1A1MAPK1CYP2C19 | |
| SCHEMBL7211832 | 0.81 | ACACB (0.36) | TSHRACACBALDH1A1MAPK1CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL31228295 | 0.80 | TSHR (0.50) | TSHRTGM2ACACBALDH1A1MAPK1 | |
| SCHEMBL10638254 | 0.80 | TSHR (0.50) | TSHRTGM2ACACBALDH1A1MAPK1 | |
| Potassium Ion SCHEMBL28817683 | 0.79 | TSHR (0.41) | TSHRTGM2ACACBALDH1A1MAPK1 | |
| Sulfuric Acid SCHEMBL10551555 | 0.79 | TSHR (0.48) | TSHRTGM2ACACBALDH1A1MAPK1 | |
| SCHEMBL9311853 | 0.77 | TSHR (0.47) | TSHRTGM2ACACBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112011011-B | Hydrophilizing coating agent composition and hydrophilized product | 日油株式会社 | 2023-05-05 | — | — | CN | disclosed |
| CN-112011011-A | Hydrophilized coating agent composition and hydrophilized product | 日油株式会社 | 2020-12-01 | — | — | CN | disclosed |
| EP-0200062-B1 | HIGH TEMPERATURE PROFILE MODIFICATION AGENTS AND METHODS FOR USING SAME | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | disclosed |
| US-4825949-A | ENHANCED OIL RECOVERY | AMERICAN CYANAMID COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| US-4746687-A | GELABLE COMPOSITIONS FOR ALTERING PERMEABILITY OF SUBTERRANEAN FORMATIONS; WATER, SULFOSUBSTITUTED ACRYLAMIDE-ACRYLIC ACID COPOLYMER, POLYVALENT METAL CROSSLINKING AGENT | AMERICAN CYANAMID COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| EP-0200062-A2 | High temperature profile modification agents and methods for using same | AMERICAN CYANAMID COMPANY (US) | 1986-11-05 | — | — | EP | disclosed |