Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 9/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617037 | 1.00 | NUDT1 (0.36) | NUDT1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8312879 | 0.83 | MAPT (0.32) | TP53CYP1A2CYP2D6TSHRTHPO | |
| SCHEMBL8312878 | 0.83 | MAPT (0.32) | TP53CYP1A2CYP2D6TSHRTHPO | |
| SCHEMBL8313155 | 0.79 | MAPT (0.45) | TP53CYP1A2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8313159 | 0.79 | MAPT (0.45) | TP53CYP1A2RAB9AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8454360 | 0.78 | MAPT (0.47) | TP53CYP1A2RAB9AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8454357 | 0.78 | MAPT (0.47) | TP53CYP1A2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8316370 | 0.76 | PTGS2 (0.41) | TP53CYP1A2CYP2D6RAB9AKDM4E | |
| SCHEMBL8316364 | 0.76 | PTGS2 (0.41) | TP53CYP1A2CYP2D6RAB9AKDM4E | |
| SCHEMBL8316367 | 0.76 | PTGS2 (0.41) | TP53CYP1A2CYP2D6RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4211089-A | — | — | None | — | — | JP | disclosed |
| JP-H04211089-A | CONDENSED THIAZOLE COMPOUND | TAKEDA CHEM IND LTD | 1992-08-03 | — | — | JP | disclosed |