Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | CCKAR | P32238 | 2/20 | 0.47 |
| ▸ | CCKBR | P32239 | 9/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617409 | 0.92 | CCKBR (0.43) | LMNATSHRCYP3A4CYP2C9HIF1A | |
| SCHEMBL9645617 | 0.88 | TRPV1 (0.39) | LMNATSHRCYP3A4CYP2C9HIF1A | |
| SCHEMBL9617418 | 0.87 | CCKBR (0.39) | LMNATSHRCYP3A4CYP2C9HIF1A | |
| SCHEMBL9646313 | 0.86 | CCKBR (0.41) | LMNATSHRCYP3A4CYP2C9HIF1A | |
| SCHEMBL9646092 | 0.79 | LMNA (0.48) | LMNATSHRCYP3A4CYP2C9HIF1A | |
| SCHEMBL9644811 | 0.78 | CCKAR (0.48) | LMNATSHRCYP3A4CYP2C9HIF1A | |
| SCHEMBL9646074 | 0.73 | CCKBR (0.44) | LMNATSHRCYP3A4CYP2C9HIF1A | |
| SCHEMBL9645604 | 0.72 | CCKBR (0.44) | LMNATSHRCYP3A4CYP2C9HIF1A | |
| SCHEMBL9646243 | 0.68 | MCHR1 (0.48) | LMNATSHRCYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL9646121 | 0.68 | MMP2 (0.43) | ALDH1A1CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4036266-A | — | — | None | — | — | JP | disclosed |
| EP-0508004-A1 | Phenylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5145869-A | Treatment of irritable bowel syndrome, dyskinesia, pancreatist; hormone inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |
| JP-H0436266-A | PHENYLSULFINYLALKYLCARBOXYLIC ACID DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1992-02-06 | — | — | JP | disclosed |