Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645565 | 0.89 | THRA (0.44) | MCHR1PLA2G2CCCKBRTHRATHRB | |
| SCHEMBL9646092 | 0.85 | LMNA (0.48) | CCKBRTHRBALDH1A1CYP2C9CYP3A4 | |
| SCHEMBL9558960 | 0.81 | CCKBR (0.46) | CCKBRALDH1A1MMP1 | |
| SCHEMBL9646313 | 0.80 | CCKBR (0.41) | MCHR1CCKBRALDH1A1CYP2C9CYP3A4 | |
| SCHEMBL9559158 | 0.79 | GAA (0.48) | CCKBRKMT2AALDH1A1LMNAMMP1 | |
| SCHEMBL9559024 | 0.79 | CCKBR (0.46) | CCKBRALDH1A1MMP1 | |
| SCHEMBL9646074 | 0.79 | CCKBR (0.44) | CCKBRTHRBALDH1A1CYP2C9CYP3A4 | |
| SCHEMBL9558525 | 0.77 | ALDH1A1 (0.43) | CCKBRALDH1A1LMNAMMP1 | |
| SCHEMBL9644737 | 0.77 | THRA (0.46) | CCKBRTHRATHRBMMP1 | |
| SCHEMBL9558853 | 0.77 | ALDH1A1 (0.43) | CCKBRALDH1A1LMNAMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508004-A1 | Phenylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5145869-A | Treatment of irritable bowel syndrome, dyskinesia, pancreatist; hormone inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |