Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463757 | 0.79 | NPC1 (0.55) | NPC1MGAT2POLBRAB9AMAPT | |
| SCHEMBL30463815 | 0.70 | NPC1 (0.74) | NPC1POLBRAB9AMAPTMAPK1 | |
| SCHEMBL9353090 | 0.67 | KMT2A (0.52) | NPC1POLBRAB9AMAPTMAPK1 | |
| SCHEMBL11309015 | 0.65 | POLB (0.60) | NPC1POLBRAB9AMAPTMAPK1 | |
| SCHEMBL11310900 | 0.65 | NPC1 (0.72) | NPC1POLBRAB9AMAPTMAPK1 | |
| SCHEMBL9353097 | 0.65 | NPC1 (0.44) | NPC1POLBRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL3836094 | 0.64 | MAPT (0.76) | NPC1POLBRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL12793742 | 0.64 | KMT2A (0.69) | NPC1POLBRAB9AMAPTALDH1A1 | |
| SCHEMBL31503975 | 0.64 | LMNA (0.78) | NPC1POLBRAB9AMAPTMAPK1 | |
| SCHEMBL3498895 | 0.64 | LMNA (0.78) | NPC1RAB9AMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4234357-A | — | — | None | — | — | JP | disclosed |
| JP-H04234357-A | AMIDOBENZENES | IMPERIAL CHEM IND PLC <ICI> | 1992-08-24 | — | — | JP | disclosed |