SCHEMBL9618285

SCHEMBL9618285

[SiH3]O[SiH](CC1CO1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 2/20 0.36
ALDH1A1 P00352 2/20 0.35
GLA P06280 1/20 0.35
CHRM2 P08172 4/20 0.35
CHRM4 P08173 4/20 0.35
CHRM1 P11229 4/20 0.35
CHRM3 P20309 4/20 0.35
CHRM5 P08912 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTR1A P08908 2/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
MGLL Q99685 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL928063 0.69 TSHR (0.33) TDP1TSHRALDH1A1
SCHEMBL630589 0.69 TP53 (0.33) TP53
SCHEMBL28241337 0.69 LOXL2 (0.33) SMN1; SMN2
SCHEMBL28032871 0.68 TDP1 (0.55) TDP1TSHRALDH1A1GLAMEN1
SCHEMBL641833 0.66 TP53 (0.31) TP53
SCHEMBL4749759 0.65 TSHR (0.37) TDP1TSHRALDH1A1SMN1; SMN2
SCHEMBL18860819 0.64 TDP1 (0.50) TDP1TSHRALDH1A1GLACHRM2
SCHEMBL1636193 0.64 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL252065 0.64 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL27996675 0.63 HTR1A (0.30) TDP1HTR1AADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4292618-A None JP disclosed
JP-H04292618-A EPOXY RESIN COMPOSITION FUJITSU LTD 1992-10-16 JP disclosed