SCHEMBL285230

SCHEMBL285230

COS(=O)(=O)[O-].C[S+](C)c1ccc(O)cc1

nearest known ligand 0.43

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
PKM P14618 1/20 0.43
ENPP2 Q13822 1/20 0.42
LMNA P02545 2/20 0.39
CA2 P00918 3/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA9 Q16790 2/20 0.38
PTGS2 P35354 1/20 0.36
CISD1 Q9NZ45 1/20 0.36
CA7 P43166 1/20 0.35
CA14 Q9ULX7 1/20 0.35
POLB P06746 1/20 0.35
GFER P55789 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL3625673 0.88 ENPP2 (0.48) GAAPKMENPP2LMNACA2
Sulfuric Acid SCHEMBL3625678 0.86 LMNA (0.48) GAAPKMENPP2LMNACA2
SCHEMBL29714721 0.86 ENPP2 (0.52) GAAPKMENPP2LMNACA2
Sulfuric Acid SCHEMBL3625676 0.81 HPGD (0.50) GAAPKMENPP2LMNACA2
SCHEMBL29402572 0.80 GAA (0.40) GAAPKMENPP2LMNAESR1
SCHEMBL4635239 0.80 HTR1A (0.38) PKMLMNACA2CA12CA9
Trifluoromethanesulfonic Acid SCHEMBL4182001 0.79 KCNH2 (0.43) GAAPKMENPP2LMNACA2
SCHEMBL9619082 0.79 MAPT (0.40) GAAPKMLMNACA2CA1
SCHEMBL245789 0.78 CYP3A4 (0.50) GAALMNACA2CA12CA1
SCHEMBL751396 0.78 ACHE (0.46) GAAPKMENPP2LMNACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2428578-B1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME EZAKI GLICO CO (JP) 2016-03-23 EP claimed
US-8575131-B2 Glucuronic acid-containing glucan, process for production of same, and use of same NATIONAL UNIVERSITY CORPORATION KAGOSHIMA UNIVERSITY (JP) 2013-11-05 US claimed
US-20120135063-A1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME EZAKI GLICO CO., LTD. (JP) 2012-05-31 US claimed
EP-2428578-A1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME National University Corporation Kagoshima University (JP) 2012-03-14 EP claimed
EP-1308475-B1 Physically foamed fine cellular polyethylene foam SAUDI BASIC IND CORP (SA) 2007-01-31 EP claimed
US-5359017-A Using an organoiron compound NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1994-10-25 US claimed
EP-0511405-A1 CATIONICALLY POLYMERIZABLE ORGANIC MATERIAL COMPOSITION AND STABILIZATION OF SAID COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1992-11-04 EP claimed
EP-0346756-B1 PROCESS FOR PRODUCTION OF SULFONIUM COMPOUNDS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-10-28 EP claimed
EP-0245662-B1 P-HYDROXYPHENYLSULFONIUM SALTS AND THEIR USE IN THE PREPARATION OF ESTERS AND AMIDES SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1991-08-07 EP claimed
US-5021197-A Reacting a p-dialkylsulfoniophenol with a carbonyl halogenide in the presence of a secondary amine MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1991-06-04 US claimed
EP-0346756-A1 Process for production of sulfonium compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-12-20 EP claimed
EP-0331988-A1 Sulfonium compounds, as well as process for producing active esters and amides used for the production of amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-09-13 EP claimed
EP-0245662-A1 p-Hydroxyphenylsulfonium salts and their use in the preparation of esters and amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1987-11-19 EP claimed
JP-1083060-A None JP disclosed
JP-1085125-A None JP disclosed
JP-6093035-A None JP disclosed
US-4857656-A Active esters used for production of esters or amides and process for producing esters or amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-08-15 US disclosed
JP-S6485125-A SURFACE ACTIVE AGENT SANSHIN KAGAKU KOGYO KK 1989-03-30 JP disclosed
JP-S6483060-A SULFONIUM COMPOUND SANSHIN KAGAKU KOGYO KK 1989-03-28 JP disclosed
EP-0245662-A1 p-Hydroxyphenylsulfonium salts and their use in the preparation of esters and amides SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1987-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120135063-A1 GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME ENGASE, FUCA1, ALG8 GAA 18/4885PKM 2264/4885ENPP2 277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.