Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 17/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393940 | 0.86 | ALKBH5 (0.57) | ALKBH5 | |
| SCHEMBL11122450 | 0.82 | ALKBH5 (0.56) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL67421 | 0.82 | ALKBH5 (0.66) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL4033097 | 0.81 | ALDH1A1 (0.57) | ALKBH5CA2KDM4EALDH1A1MAPT | |
| SCHEMBL27752106 | 0.81 | ALDH1A1 (0.57) | ALKBH5CA2KDM4EALDH1A1MAPT | |
| SCHEMBL11218444 | 0.81 | CA2 (0.39) | ALKBH5CA2KDM4EALDH1A1MAPT | |
| SCHEMBL11124699 | 0.81 | ALKBH5 (0.58) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL692998 | 0.81 | ALKBH5 (0.64) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL9176966 | 0.78 | ALKBH5 (0.61) | ALKBH5KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL1265713 | 0.77 | ALKBH5 (0.60) | ALKBH5KDM4EALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279277-B1 | WATER SOLUBLE MONOAZO-PYRAZOLONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-06 | — | — | EP | disclosed |
| EP-0292904-B1 | WATER SOLUBLE NAPHTYL-AZO-PYRAZOLON COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-12 | — | — | EP | disclosed |
| US-4963661-A | MONOAZO DYES; FAST YELLOW TO ORANGE HUES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-16 | — | — | US | disclosed |
| US-4960872-A | FOR DYEING CELLULOSE FIBERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| US-4916215-A | Water-soluble disazo compounds containing substituted triazinyl radical, pyrazole-type groups, and a plurality of fiber-reactive sulfone-containing groups, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-10 | — | — | US | disclosed |
| EP-0292904-A2 | Water soluble naphtyl-azo-pyrazolon compounds, process for their preparation and their use as dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |