SCHEMBL9619922

SCHEMBL9619922

CC(Cl)S(=O)(=O)c1c(Cl)nc(Cl)nc1Cl

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9619932 0.86 L3MBTL1 (0.32) GAATDP1ALDH1A1ALOX15TSHR
SCHEMBL10785633 0.84 ALDH1A1 (0.32) ALDH1A1ALOX15TSHR
SCHEMBL10787102 0.75
SCHEMBL9619744 0.73 ALDH1A1 (0.35) GAAALDH1A1ALOX15TSHR
SCHEMBL9619772 0.70 LMNA (0.33) ALDH1A1ALOX15TSHR
SCHEMBL9620025 0.65
SCHEMBL9340350 0.65
SCHEMBL9619816 0.65 CASP1 (0.32)
SCHEMBL9340351 0.65 GLP1R (0.38) GAAALDH1A1
SCHEMBL9619836 0.65 ALDH1A1 (0.32) ALDH1A1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0285571-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-02-05 EP disclosed
US-4968781-A COTTON CIBA-GEIGY CORPORATION (US) 1990-11-06 US disclosed
US-4709018-A COLORFAST CIBA-GEIGY CORPORATION (US) 1987-11-24 US disclosed
US-4680384-A PYRIMIDINE DYES CIBA-GEIGY CORPORATION (US) 1987-07-14 US disclosed
US-4325869-A CONTAINING A PYRIMIDINE RING AND ONE OR MORE AZO GROUPS CIBA-GEIGY CORPORATION (US) 1982-04-20 US disclosed