Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675124 | 0.92 | ADRA1A (0.68) | ADRA1APDE4DMAPTTP53 | |
| SCHEMBL8055886 | 0.83 | ADRA1A (0.82) | ADRA1APDE4D | |
| SCHEMBL9521958 | 0.81 | ADRA1A (0.34) | ADRA1APDE4DMAPTTP53 | |
| SCHEMBL8531170 | 0.76 | ADRA1A (0.46) | ADRA1APDE4DMAPT | |
| Malotilate SCHEMBL635496 | 0.73 | ADRA1A (1.00) | ADRA1APDE4D | |
| SCHEMBL8385459 | 0.73 | ADRA1A (0.50) | ADRA1APDE4DMAPT | |
| SCHEMBL17266586 | 0.72 | MAPT (0.39) | MAPTTP53 | |
| SCHEMBL9524421 | 0.71 | ADRA1A (0.41) | ADRA1APDE4DMAPT | |
| SCHEMBL9673295 | 0.71 | SOAT1 (0.44) | ADRA1APDE4DMAPT | |
| SCHEMBL10385307 | 0.71 | GRIK1 (0.38) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1992-08-26 | — | — | EP | disclosed |
| EP-0310109-B1 | NOVEL AMINOALKYL-SUBSTITUTED HETEROCYCLIC SULFUR COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-08 | — | — | EP | disclosed |
| EP-0310109-A2 | Novel aminoalkyl-substituted heterocyclic sulfur compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-04-05 | — | — | EP | disclosed |
| EP-0298040-A1 | 1,3-Dithiol-2-ylidene derivatives | YUHAN CORPORATION, LTD. (KR) | 1989-01-04 | — | — | EP | disclosed |