Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838746 | 0.91 | ESR1 (0.45) | ESR1ESR2ALDH1A1TSHRCYP2C9 | |
| SCHEMBL10977710 | 0.87 | CA2 (0.47) | LPLLIPGESR1ALDH1A1HPGD | |
| SCHEMBL24021959 | 0.84 | HTR2A (0.56) | LPLLIPGESR1ALDH1A1TSHR | |
| SCHEMBL28827751 | 0.84 | HTR2A (0.56) | LPLLIPGESR1ALDH1A1TSHR | |
| SCHEMBL10017779 | 0.83 | CA2 (0.46) | ESR1ESR2ALDH1A1TSHRCYP2C9 | |
| SCHEMBL5665155 | 0.83 | MAOA (0.45) | ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL1611359 | 0.83 | ALDH1A1 (0.40) | ESR1ESR2ALDH1A1TSHRCYP2C9 | |
| SCHEMBL10130853 | 0.83 | LPL (0.45) | LPLLIPGACACBESR1ESR2 | |
| SCHEMBL6182941 | 0.83 | TAAR1 (0.54) | LPLLIPGACACBESR1ESR2 | |
| SCHEMBL598140 | 0.83 | ALDH1A1 (0.52) | ESR1ESR2ALDH1A1TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814486-B1 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION | KINETA FOUR LLC (US) | 2018-04-11 | — | — | EP | disclosed |