Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992410 | 0.87 | — | — | |
| SCHEMBL4778396 | 0.73 | LMNA (0.40) | LMNACYP2A6IDO1MAOAMAOB | |
| SCHEMBL10765712 | 0.71 | CA1 (0.46) | LMNAIDO1MAOAMAOBSLC6A4 | |
| 1,4-Dichlorobenzene SCHEMBL11243685 | 0.62 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL5191 | 0.62 | — | — | |
| SCHEMBL668905 | 0.60 | SLC6A4 (0.47) | LMNACYP2A6MAOAMAOBKDM1A | |
| SCHEMBL28574237 | 0.59 | MAOA (0.40) | LMNACYP2A6IDO1MAOAMAOB | |
| SCHEMBL9735920 | 0.58 | CCNB2 (0.47) | LMNACYP2A6MAOAMAOBKDM1A | |
| 1,4-Dichlorobenzene SCHEMBL5144812 | 0.58 | LMNA (0.89) | LMNACYP2A6IDO1 | |
| 1,4-Dichlorobenzene SCHEMBL10603593 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236074-B1 | 2BETA-SUBSTITUTED THIOMETHYLPENICILLIN DERIVATIVES AND THEIR PREPARATION AND USE | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4861768-A | 2 β-substituted thiomethylpenicillin derivatives and their preparation and use | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0236074-A1 | 2Beta-substituted thiomethylpenicillin derivatives and their preparation and use | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1987-09-09 | — | — | EP | disclosed |